Prostadine reviews also known as prostaglandin E1 and colloquially as PGE1, is a naturally occurring prostaglandin with a variety of biological functions. Prostaglandins are involved in a wide range of physiological processes, including regulation of the cardiovascular system and in the immune system. They are synthesized from arachidonic acid by cyclooxygenases (COX) enzymes.
Prostaglandins are structural analogues to thromboxane A2, which has been implicated in platelet aggregation. Their function is to regulate inflammation, haemostasis and other biological activities in vertebrates. Prostaglandins act through G protein-coupled receptors that are found on target cells. A number of prostaglandins have been identified by their effects on specific organs or tissues or through specific receptors.
Prostacyclin (PGI2) is a potent vasodilator that acts via prostanoid receptors PGI2 (IP receptor) and IP receptor (IPR). PGI2 also acts as an antiatherosclerotic agent by inhibiting platelet adhesion to arterial walls through inhibition of thromboxane A2 production.
