Cenforce Soft, a medication primarily used to treat erectile dysfunction, contains sildenafil citrate as its active ingredient. Cenforce Soft works by increasing blood flow to the penis during sexual stimulation. When considering interactions with over-the-counter (OTC) medications, caution is necessary. Some OTC drugs, such as certain antihistamines, decongestants, or herbal supplements like St. John’s Wort, may affect how sildenafil works or increase the risk of side effects like dizziness or low blood pressure. Additionally, combining Cenforce Soft with nitrates (often prescribed but sometimes available OTC in some countries) can cause dangerous drops in blood pressure. It’s important to consult a healthcare provider before mixing Cenforce Soft with any OTC medication to avoid adverse effects and ensure safe use.