Vigora 50 mg, as it contains Sildenafil (the same active ingredient found in Viagra). Sildenafil is metabolized by the liver, and if your liver is not functioning properly, the medication can accumulate in your system, leading to an increased risk of side effects. Key Considerations for Liver Issues: Liver Metabolism: Sildenafil is primarily broken down by the liver enzyme CYP3A4. If you have liver impairment, your body may take longer to process and eliminate the drug, which   Vigora 50 mg lead to higher blood levels of sildenafil and a greater likelihood of side effects (like headache, dizziness, or low blood pressure). Moderate to Severe Liver Impairment: Avoid Vigora or Use with Caution: If you have moderate or severe liver problems (such as cirrhosis or liver failure), you should avoid taking Vigora 50 mg unless specifically directed by a healthcare provider. If prescribed, your doctor will likely reduce the dose and monitor you closely for any side effects. Mild Liver Impairment: If you have mild liver dysfunction, your doctor may still prescribe Vigora 50 mg, but adjust the dosage to a lower amount, typically starting at 25 mg rather than 50 mg. This helps prevent the drug from building up in your system. When to Avoid Vigora 50 mg Completely: Severe liver disease: If you have conditions like advanced liver cirrhosis or active liver disease, you should avoid using Vigora 50 mg unless directed by a healthcare provider.