Vidalista 60 mg is a high-dose tadalafil used to treat erectile dysfunction (ED). For men with diabetes, there are specific situations where this high dose may not be suitable. Here’s a detailed explanation: 1. Why men with diabetes need caution Diabetes can cause nerve and blood vessel damage (diabetic neuropathy and vascular problems), which may already affect blood pressure, kidney function, and heart health. High-dose tadalafil can impact these systems, so extra caution is needed. 2. Situations where Vidalista 60 mg is not suitable Condition Reason Severe cardiovascular disease (recent heart attack, unstable angina, heart failure) Tadalafil can lower blood pressure and increase cardiac stress. Low blood pressure or uncontrolled hypertension High-dose PDE5 inhibitors can worsen hypotension or hypertension. Kidney or liver impairment High-dose tadalafil is metabolized by the liver and excreted by the kidneys; accumulation can increase side effects. Taking nitrates (for chest pain) Dangerous interaction: can cause life-threatening drop in blood pressure. Retinopathy or vision issues Diabetes-related eye problems plus tadalafil may increase the risk of vision complications. Other medications affecting blood pressure or heart function Risk of dizziness, fainting, or serious hypotension. 3. Other precautions Men with mild-to-moderate diabetes and stable heart health may tolerate lower doses (10–20 mg or 40 mg) better than 60 mg. Always start with the lowest effective dose under medical supervision. Monitor for side effects like dizziness, chest pain, prolonged erection, or vision changes.   Vidalista 60 mg is not suitable for men with diabetes who have heart problems, low blood pressure, kidney/liver issues, or take nitrates. Even if those conditions aren’t present, high-dose tadalafil should only be used under strict medical guidance, and lower doses are usually safer for diabetic men. If you want, I can make a quick chart showing safe tadalafil dose ranges for diabetic men based on their health status.