What is addyi?
Flibanserin is a modulator of the 5-HT receptor that is used in the treatment of some premenopausal female patients who suffer from widespread, acquired, hypoactive sexual drive problem (HSDD).
In August of 2015, the FDA granted permission to the first medicine, flibanserin, to treat premenopausal women who suffer from hypoactive sexual desire disorder (HSDD). Flibanserin was among the first pharmaceuticals to get this approval. Initially, this medicine was functioning as an antidepressant; however, over the course of time, it did not result in adequate efficacy throughout numerous studies; as a consequence, it was eventually adjusted to function as a therapy for hypoactive sexual dysfunction. Flibanserin's mechanism of action is related to its close affinity with 5-HTA1 and 5-HTA2 receptors. It exhibits agonist action on 5-HTA1 and antagonist action on 5-HTA2, which causes a reduction in serotonin levels in the brain while simultaneously increasing the amounts of dopamine and norepinephrine neurotransmitters.
The Workings of the Flibanserin Action Mechanism
In addition to the aforementioned affinity of flibanserin for serotonin receptors located inside the brain, it also interacts in a manner that is analogous to that of 5-HT1A and 5-HT2A receptors. On the other hand, when there are higher amounts of 5-HT in the brain (for example, during times of elevated stress), flibanserin may occupy 5-HT2A receptors in a greater percentage as compared to 5-HT(1A) receptors. In addition to this, there is some speculation that flibanserin may also exert a moderately antagonistic effect on dopamine D4 receptors, in addition to 5-HT2B and 5-HTB2C receptors. Because of the way it interacts with neurotransmitter receptors, it has the potential to lower serotonin levels while simultaneously elevating norepinephrine and dopamine concentrations. This can lead to an improvement in the patient's response to treatment.
After receiving Flibanserin, patients should wait at least six hours before driving or engaging in any other tasks that need their whole attention, such as operating heavy machinery or operating hazardous machinery. A combination of flibanserin with CNS depressants, such as opioids, diphenhydramine, benzodiazepines, or hypnotics, should be avoided at all costs. Syncope and low blood pressure are two side effects that may happen from taking flibanserin by itself.
There has been a dose-associated rise in the number of instances of malignant mammary tumors seen in female mice, according to a number of studies conducted on mice (exposure levels 3 and 10 times higher than the suggested clinical dose). This impact was not seen in male mice, nor in male or female rats of any species.
It is strongly recommended that you only purchase addyi from recognized and reliable pharmacies and only with a prescription from a medical professional. There is no doubt that your healthcare provider will recommend the most appropriate pharmacy for you, but in addition to asking them, you can also conduct your own research online in order to identify reputable online pharmacies. In addition, you can save time searching by purchasing Flibanserin from our pharmacy (name of pharmacy), which has a long history of working in the pharmaceutical market and has already earned a very good reputation among customers and companions. This will allow you to save time searching for the medication.
